In this insightful presentation at ISIC 2022, Lou Cozolino delves into the fascinating evolution of the brain, emphasizing the interconnectedness of its primitive and advanced regions. Cozolino discusses how the brain's social functions developed from basic survival mechanisms, with attachment and social behaviors deeply rooted in our neural circuitry. Highlighting the necessity of stimulation and connection for brain growth, he underscores the significance of social interactions and relationships. Cozolino also explores the critical role of early experiences and attachment in brain development, drawing on studies of children in various environments. By examining the deep biological foundations of social behaviors, this talk sheds light on the importance of nurturing social environments for healthy brain development.